Influence of m-trihydroxybenzene on the recurrence rate in children with intussusception hydrostatic enema

Abstract

Objective To explore the application value of m-trihydroxybenzene in pediatric intussusception in the course of treatment,to observe its curative effect and safety.Methods 200 cases of enema intussusception were selected and randomly divided into two groups by the method of random number table.100 cases in the observation group were given m-trihydroxybenzene injection (2mg/kg) 15 minutes before hydrostatic enema,and reduction of hydrostatic enema.If reduction,continued to give benzene three phenol intravenous drip,once a day.100 cases in the control group used atropine(0.02mg/kg) intramuscular injection before hydrostatic enema,after successful reduction did not continue to use the spasmolytic drug.The success rate,short-term recurrence rate,reduction time and adverse reaction were compared between the two groups.Results The hydrostatic pressure enema reduction success rate of the observation group was 99％,which was significantly higher than 87％ in the control group (x2 =4.38,P ＜ 0.05).The reduction time of the observation group was (7.56 ± 2.54) min,which was significantly shorter than (10.45 ± 3.03) min of the control group (t =-4.285,P ＜ 0.05).The short-term recurrence rate in 3 days of the observation group was 3％,which was significantly lower than 13％ in the control group (x2 =2.79,P ＜0.05).The observation group had no obvious adverse reaction.Conclusion m-Trihydroxybenzene in water enema intussusception reset before and after use is safe and effective,it can not only improve the success rate reduction,but also can significantly reduce the short-term recurrence of intestinal intussusception reduction rate. Key words: Phloroglucinol; Intussusception; Enema; Ultrasonography; Child