Influence of gallbladder condition on parameters of electrocardiography, echocardiography and coronaroangiography

Abstract

Precise criteria of cholecystocardial syndrome according to results of electrocardiography (ECG), echocardiography (EchoCG) and coronaroangiography (CAG) are not established yet. That’s why the aim of our paper was to identify typical changes in ECG, EchoCG and CAG in dependence of gallbladder (GB) condition. We analyzed data of 98 patients with clinically and instrumentally verified diagnosis of ischemic heart disease (40% — acute myocardial infarction, 60% — angina pectoris), 79% males and 21% females, mean age 61,7±1,6 years. Patients were divided into groups according to GB condition, assessed by ultrasound (intact GB, n=29; sludge and cholesterosis, n=13; bent GB body, n=13; GB neck deformations and cholecystitis, n=27; cholelithiasis, n=11; past cholecystectomy, n=5). All parameters were compared to values of intact GB group, which were taken as 100%. It was established that histograms of structural and functional condition of heart were dependant of GB disorder. In patients with different GB conditions main changes of heart and coronary vessels were mainly related to the frequencies of rhythm and conductivity disorders, ST interval depressions, signs of left ventricle hypertrophy, hypokinetic zones detection, different types of blood supply, qualitative and quantitative characteristics of main coronary arteries abnormalities. Heart changes were alike in patients with cholelithiasis and past cholecystectomy, and in patients with sludge and bent GB body. Heart rate, EchoCG parameters of heart structure and ejection fraction were almost not dependant of GB condition.