Abstract
A method is presented for dissolution-rate studies based on three-dimensional movement of the dissolution cell around its axis. By using this agitating system, the solute flux from benzoic acid and iodine disks was studied at different flow velocities. The results obtained were compared with the rotating-disk method. The dependence of dissolution rate on the power of flow velocity and on the activation energy was determined experimentally. The Reynolds and Peclet numbers were calculated from the parameters of the experiments, and the values obtained were compared with theory for laminar and turbulent flow.
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