Abstract

The purpose of this study was to examine the influence of physical activity level of men and women on VLDL subfractions and lipoprotein (a). Fifty-four men (n=30) and women (n=24), ages 30-53, were recruited based on their level of activity over the past two years and formed three groups: sedentary (S), no routine activity; recreational exercise (R), routine moderate exercise 3-5 times per week; and trained (T), competition based intense aerobic training, 5-7 times per week. Each subject performed a maximal oxygen consumption test and was measured for body composition (skinfolds) and waist to hip (W/H) ratio. Following a prescribed 24 h diet and abstinence from activity, each subject had blood drawn and plasma analyzed for cholesterol and triglycerides in VLDL1, VLDL2, and VLDL3 subfractions. HDL-C also was analyzed. Total VLDL-C was higher in men than women, but no gender differences were observed in VLDL subfractions. VLDL1-TG and VLDL2-TG were elevated in the S group compared to R and T, even though total VLDL-TG values were not different among the groups. W/H ratio was different between the S and T groups. The two exercising groups were not different on any lipoprotein variable or W/H ratio. VLDL1-TG was inversely correlated to maximal oxygen consumption and HDL-C. These results suggest that lifestyle activity is associated with a favorable VLDL subfraction pattern and W/H ratio. In addition, lifestyle recreational activity is associated with a similar lipoprotein profile and W/H ratio as vigorous, competitive exercise training.

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