Abstract
A study of the quantitative effect of type of binder (N), applied pressure (P), and granular size (G) on two mechanical properties–tensile strength (TS) and brittle fracture index (BFI)—of a sulfadimidine tablet formulation has been carried out by using a 23 factorial experimental design. The results obtained from this work suggest that P exhibited the largest individual effect on TS and BFI. It is also seen from this work that the nature of binders in combination affects the influence that P and G had on the TS or BFI.
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