Abstract
6701 Background: The antigen-drive association of gastric MALT lymphoma with H. pylori is well recognized. Successful antibiotic therapy can result in lymphoma remission, and with it, lymphoma prevention. We have sought to prospectively identify possible associated infections (candidates for antigen-drive) in patients with non-bulky, advanced stage indolent lymphoma as the first step to such a lymphoma treatment/ prevention strategy. These patients are often given a recommendation of monitoring (“watch and wait”) and it is during this period that a window of opportunity may exist to identify and treat antigen-drive related infections. Methods: Patients with a new diagnosis of indolent lymphoma (FL and nFL), stages II (intra-abdominal), III and IV fulfilling GELF criteria for observation were eligible. Studies performed: Stool H. pylori, Hepatitis C and Borrelia serologies, Borrelia and Chlamydia fixed tissue PCR, peripheral blood mononuclear cell PCR for Chlamydia, and a hydrogen breath test for small bow...
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