Abstract

Highly kinetically inert paramagnetic platform shows outstanding CEST properties suitable for advantageous MRI applications.

Highlights

  • Efficient detection and monitoring of pathological processes is a key step in ensuring the timely diagnosis of numerous diseases

  • We report on a macrocyclic platform based on an 18-membered macrocycle that forms kinetically highly inert paramagnetic complexes and possesses an excellent outlook for the development of bioresponsive paraCEST contrast agents

  • We have reported on a paramagnetic platform that forms kinetically highly inert complexes and has an excellent outlook for the development of entirely new class of paraCEST probes

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Summary

Introduction

Efficient detection and monitoring of pathological processes is a key step in ensuring the timely diagnosis of numerous diseases.

Results
Conclusion

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