Abstract
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants (WHO 1993). They accumulate in the fatty tissues of humans and other animals and have caused toxic effects in both (Safe 1987). Surface water may become contaminated with PCBs from atmospheric fall-out or from direct point sources. Fish have been shown to take up PCBs readily from water, while their bioconcentration factors are rather high. There have been many suggestions in the literature that PCBs might affect populations of fish in the wild. Studies attempting to demonstrate such an effect are few. In the present study, the incidence of micronuclei in the peripheral erthrocytes of Misgurnus anguillicaudatus treated with contaminated water by commercial PCBs was analyzed. The aim of the experiment is to use a model test system for rapid assessment of the genotoxicity of PCBs in aquatic environment. 9 refs., 2 tabs.
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