Abstract
Anemia is a very common blood disorder that affects the lives of billions of people worldwide. Anemia is caused by the loss of blood, increased destruction of red blood cells...
Highlights
Red blood cells (RBCs) are the most abundant cells in our circulatory system
Very little is known about the role of deubiquitinating enzymes (DUBs) in erythropoiesis
Our results suggest that ubiquitin-specific protease 50 (USP50) indirectly regulates the stability of the Ku70, which is a DNAbinding protein, and is expressed in CD34+ hematopoietic progenitor cells (HPCs).[18]
Summary
Red blood cells (RBCs) are the most abundant cells in our circulatory system. RBCs are highly specialized to transport oxygen, bound to intracellular hemoglobin, from the lungs to the rest of the body. RBCs are responsible for maintaining normal tissue oxygenation and preventing systemic and cellular hypoxia. Anemia is a very common disorder that results from decreased numbers of circulating RBCs or a decreased capacity of RBCs to carry oxygen. The symptoms felt by patients with anemia are related to systemic hypoxia. Conditions such as blood loss, hemolysis, iron deficiency, vitamin deficiencies, and chronic inflammation are common causes of anemia.[12]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
