Abstract

Bacteriophages which survive the direct effects of irradiation exhibit nonlethal damage. Thus an extended latent period has been shown after ultraviolet irradiation by Luria (1) and after X-irradiation by Pollard et al. (2). The latter authors have suggested that the existence of both lethal and nonlethal effects may be due to the presence of two kinds of units within the phage structure-one kind vital for phage reproduction, and the other nonessential but important in determining the rates of the various steps involved in reproduction. Present knowledge does not allow an identification of such units with specific phage sites or functions, nor can it be said whether each unit or function consists of only one or a multiplicity of biological or biochemical entities.

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