Abstract
BackgroundIn China, the incidence of Inflammatory bowel disease (IBD) has shown a significant growth trend. Analysis of the epidemiology, clinical manifestations, diagnostic means, and treatment of IBD will further improve the clinician's understanding of IBD, improve knowledge and further enable early diagnosis and standardized therapeutic management. The purpose of this study was to analyze the clinical characteristics of IBD inpatients in General Hospital of NingXia Medical University over a 12-year period to identify trends in clinical and epidemiological features, clinical manifestations, and treatment programs.MethodsBy excluding188 patients with incomplete information or incompatible with the 2012 Guidlines cases, we retrospectively analyzed the case records of 567 inpatients with a diagnosis of IBD admitted to the General Hospital of NingXia Medical University between January 2002 and December 2014. The clinical epidemiological features, clinical manifestations, diagnostic methods, and therapeutic status were analyzed.ResultsOver the study period, IBD hospitalization rates in 2002 and 2014 groups was 1.96 % and 4.05 %, increased 2.07 times. Of 567 cases of IBD, 483 (85.19 %) cases were categorized as ulcerative colitis (UC) and 84 as Crohn’s disease (CD) (14.81 %). Total male cases were 321 (56.61 %). Mean age of cases was 49.06 ± 14.92 years for UC and 44.84 ± 14.67 years for CD. The majority of UC was located in the colon, with a moderate level of disease activity. A combination of clinical manifestations and colonoscopy was mostly used to make a diagnosis; relatively the rate of pathological diagnosis was low, with a small proportion of patient’s diagnosed based on radiology. Treatment with SASP/5ASA and steroids was applied to the majority of inpatients and 47.83 % were treated with antibiotics; in contrast, only 1.86 % cases were treated with immunosuppressive therapy.ConclusionsAn increasing trend of admissions for IBD can be observed in our study; there are some differences in clinical features and treatment compared with Western countries, and further research into this is required.
Highlights
In China, the incidence of Inflammatory bowel disease (IBD) has shown a significant growth trend
The aim of this study was to analyze clinical characteristics such as epidemiology, method of diagnosis, and treatment of hospitalized patients with IBD, over a 12-year period at the General Hospital of NingXia Medical University, which is the largest and has a degree of representivity in the region. These data would be a useful observation of the increase in IBD incidence and prevalence in China, and provide valuable information for the proper diagnosis and management of the disease. In this retrospective survey we reviewed the medical records of inpatients with IBD admitted to the General Hospital of NingXia Medical University between January 2002 and December 2014
Hospitalization rates A total of 567 patients, including 483 with Ulcerative Colitis (UC) (85.19 %) and 84 with Crohn’s Disease (CD) (14.81 %), were examined from 2002 to 2014
Summary
In China, the incidence of Inflammatory bowel disease (IBD) has shown a significant growth trend. Clinical manifestations, diagnostic means, and treatment of IBD will further improve the clinician's understanding of IBD, improve knowledge and further enable early diagnosis and standardized therapeutic management To this end, the Chinese Medical Association of Gastroenterology has developed a researchbased consensus opinion on the diagnosis and treatment of IBD, published and updated in 1978, 1993, 2000, 2007, and 2012. The Chinese Medical Association of Gastroenterology has developed a researchbased consensus opinion on the diagnosis and treatment of IBD, published and updated in 1978, 1993, 2000, 2007, and 2012 These revisions are dependent on the analysis of clinical data from Western countries due to a lack of largescale epidemiological, clinical studies and an inadequate follow-up system in China. China is in urgent need of more multi-center, well-designed clinical research in order to develop treatment guidelines based on local conditions
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
