Abstract

An attempt was made to induce physical dependence in rats by restricting their fluid intake to concentrations of alcohol that were increased from 5–20% during 4 months. Alcohol intake decreased during the month that the 20% concentration was available. Following alcohol withdrawal water was consumed in significantly greater amounts than in control rats on the first and fourth through twelfth days thereafter. It is doubtful that this was due to abstinence. A fluid deficit might have developed during the last month on alcohol so that an increase in water consumption occurred when it became available.

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