Incorporation of CPP-ACP into Luting and Lining GIC: Influence on Wear Rate (in the Presence of Artificial Saliva) and Compressive Strength.

Abstract

The improvement of mechanical and antibacterial properties of glass ionomer cements (GICs) is an important goal in dental research. In this way, modification of GIC with caries preventive and remineralizing materials such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is a new strategy to enhance its anticariogenic properties and the remineralization of teeth. However, one main concern is that adding CPP-ACP may have negative effects on the mechanical properties of GIC. This study investigated the influence of adding CPP-ACP on the wear rate (in the presence of artificial saliva) and compressive strength of luting and lining glass ionomer cement. CPP-ACP was incorporated into a luting and lining glass ionomer cement at different percentages (1, 1.56, and 2%). Wear rate and compressive strength were measured for each group using Pin-on-Disk tribometer device (in artificial saliva condition) and universal testing machine, respectively. The wear test was carried out in the presence of artificial saliva for better simulation of the oral environment. Our results demonstrated that increasing the percentage of CPP-ACP from 0 up to 1.56% (w/w), caused a decrease of 19% in the wear rate. However, at 2% (w/w) CPP-ACP, the wear rate increased. Compressive strength was improved by 31% when the CPP-ACP concentration was increased to 1.56% (w/w), but decreased when the concentration was raised to 2% (w/w). In conclusion, adding 1.56% CPP-ACP into luting and lining glass ionomer cement appears to provide an acceptable combination of two important mechanical properties, compressive strength and wear rate.