Abstract
Myasthenia is thought to be rare in infants; three different types may occur. The authors present three children aged four, five and six years with an incomplete external ophthalmoplegia as the initial and only sign of ocular infantile myasthenia. In one child the ptosis and ophthalmoplegia were unilateral, in the other, bilateral and slightly asymmetric. All three children had typical lid twitch at upgaze. Computed tomographic (CT) scans of the brain and orbit yielded normal results. Dramatic improvement of motility and ptosis after intravenous injection of edrophonium chloride was useful for a decisive diagnosis.
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