Abstract
In this paper, we evaluate the relative performance of competing approaches for estimating phylogenies from incomplete distance matrices. The direct approach proceeds with phylogenetic reconstruction while ignoring missing cells, whereas the indirect approach proceeds by estimating the missing distances prior to phylogenetic analysis. Two distinct indirect procedures based on the ultrametric inequality and the four-point condition are further compared. Using simulations, we show that more reliable results are obtained when such indirect methods are used. Expectedly, the phylogenies become less accurate as the percentage of missing cells increases, but combining different estimation methods greatly improves the accuracy. An application to bat phylogeny confirms the results obtained in the simulation study and illustrates the effect of missing distances in the construction of supertrees.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
