Incidencia de eventos tromboembólicos venosos en pacientes hospitalizados con COVID-19

Abstract

Background and objectiveSeveral studies have reported on the thromboembolic alterations developed in patients with SARS-CoV-2 pneumonia, however, there are no definitive data on the risk factors for the appearance of these events. The aim of this study was to analyse the relationship between personal, clinical, and paraclinical factors and the development of venous thromboembolic complications in hospitalized patients with COVID-19. MethodsFollow-up study of a retrospective cohort of COVID-19 patients admitted, from August 2020 to February 2021, to the Clínica Antioquia de Itagüí. 525 medical records of patients older than 18 years with a confirmed diagnosis of SARS-CoV-2 were included. ResultsThe presence of VTE was identified in 3% of hospitalized patients. Of the patients with COVID-19, 25.1% were admitted to the intensive care unit, 18.9% required invasive mechanical ventilation. Mortality from COVID-19 in our study was 18.1%. In patients hospitalized with SARS-CoV-2, an increased risk of development of thromboembolic events was identified in those with elevated levels of troponin I (HR 4.07; 95% CI 1.09-15.18), a history of prior thromboembolic events (HR 11.01; 95% CI 1.06-114.87), and thrombocytopenia (HR 6.47; 95% CI 2.05-20.44). ConclusionsAn association was found between thromboembolic complications and a history of VTE. Likewise, it was concluded that troponin values ≧ .03 ng/ml and platelet levels < 150,000/mm3 are associated with VTE.