Incidence of mortality in vulnerable and non-vulnerable older patients with cancer.

Abstract

e13775 Background: Cancer most often affects older adults; 56% of all newly diagnosed cancer patients and 71% of deaths belong to this age group. Frail patients are at increased risk of unfavorable outcomes after Treatment. Methods: This cross-sectional study included adults older than ≥ 65 years who attended the Oncology department were included, with a diagnosis of a solid malignant neoplasm during March 2022-May 2023. Sociodemographic characteristics and characteristics of the disease were evaluated, and the G8 test was applied, a tool that identifies patients at risk of frailty (nutritional status, mobility, age, general health status, neuropsychological status, drugs used); a score ≤14 indicates that they are vulnerable. They were classified into two groups: group 1 (vulnerable) and group 2 (non-vulnerable). Telephone follow-up was performed at 12 and 24 weeks. We evaluated the incidence of mortality in both groups after oncological medical management. Results: Eighty-eight older adults were recruited, the majority were men (77.3%), and the mean age was 74.2 ± 6.71. Forty-seven patients (53.4%) were vulnerable (group 1), and 41 patients (46.6%) were non-vulnerable (group 2). Mortality at 12 weeks was evaluated: vulnerable (29.8%) vs. non-vulnerable (0%), and mortality at 24 weeks: vulnerable (46%) vs. non-vulnerable (4.9%). In both follow-ups, statistically significant results were obtained (<0.001). Conclusions: Vulnerable patients have a higher risk of unfavorable outcomes; their detection is essential to perform a comprehensive geriatric assessment and provide multidisciplinary treatment, improving the prognosis of their disease. [Table: see text]