Abstract

Background: Acute kidney injury (AKI) is a common complication in critically ill patients and it is commonly associated with high mortality and morbidity with adverse short and long term outcome. Objectives: The main objective of this study was to determine the incidence of acute kidney injury in ICU patients in Omdurman teaching hospital, and to assess the risk factors associated with the development of acute kidney injury in a critically ill patient. We also intended to find out the impact of acute kidney injury on ICU outcomes. Methods: In this descriptive prospective, cohort hospital-based study, 211 patients were studied and followed up during admission in ICU from November 2019 until July 2020 in Omdurman teaching hospital. Results: 61 patients of the total 211 patients developed renal impairment during their stay in ICU. 64% (39 patients) were males and 36% (22 patients) were female, mean age was 41 ± 5, renal impairment developed after a mean of 5 days of admission and the most common cause was decreased level of consciousness and severe hypotension, sepsis accounting for 40% of the admission. The outcome in ICU showed that the mortality rate was high up to 41% in patients who developed acute kidney injury, Sepsis accounted for over 96% (24 patients) who have passed away. Conclusions: Development of AKI in ICU is an important risk factor for poor outcomes in critically setting. Prevention is the best method for avoiding AKI, with the early identification and recognition of high-risk patients.

Highlights

  • IntroductionEltahir (ICU) and is commonly associated with adverse outcomes, increasing the length of intensive care unit (ICU) stay, increasing short and long term mortality, and contributing to developing chronic kidney disease (CKD)

  • The main objective of this study was to determine the incidence of acute kidney injury in intensive care unit (ICU) patients in Omdurman teaching hospital, and to assess the risk factors associated with the development of acute kidney injury in a critically ill patient

  • Prevention is the best method for avoiding Acute kidney injury (AKI), with the early identification and recognition of high-risk patients

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Summary

Introduction

Eltahir (ICU) and is commonly associated with adverse outcomes, increasing the length of ICU stay, increasing short and long term mortality, and contributing to developing chronic kidney disease (CKD). The identification and studying of the risk factors associated with the development of acute kidney injury will help in providing and establishing preventive measure that could improve survival in those patients. As recognition of those high-risk patients will allow developing steps and guidelines help in prevention, diagnosis and treatment of AKI. Acute kidney injury is preventable and treatable in most cases, it carries a high mortality rate in a critical care setting, especially in developing countries. This research was focused on the frequency, risk factors, and outcome

Literature Review
Risk Factors
Rationale
Study Area
Data Collection Techniques
Ethical Consideration
Data Analysis
General Patient Characteristics
Renal Impairments
Discussion
Findings
Conclusions
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