Abstract
The sequence of cytotoxic effects for a series of mercury compounds to the BG/F epithelioid cells derived from fin tissue of bluegill sunfish was phenyl mercuric chloride > methyl mercuric chloride > ethyl mercuric chloride ⪢ mercuric chloride. This sequence of in vitro cytotoxicity was similar to that observed in a 48-h LC 50 in vivo acute toxicity assay with rainbow trout. Using induction of micronuclei as an indicator of genetic damage, the organomercurials, but not mercuric chloride, were noted to be clastogenic to the BG/F cells.
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