Abstract
Comparative estimations of the antioxidant activity of methanolic extracts from biomasses of different types of in vitro cultures of Cistus × incanus, Verbena officinalis, Scutellaria lateriflora, and S. baicalensis and also from plant raw materials were performed. The antioxidant measurements were based on the modern assays—cupric ion reducing antioxidant capacity (CUPRAC) and quick, easy, new, cheap, and reproducible CUPRAC (QUENCHER-CUPRAC). The total extractable antioxidants (CUPRAC assay) ranged from 10.4 to 49.7 mmol (100 g)−1 of dry weight (DW) expressed as Trolox equivalent antioxidant capacity (TEAC), and the global antioxidant response (QUENCHER-CUPRAC assay) ranged from 16.0 to 79.1 mmol (100 g)−1 DW for in vitro cultures, whereas for plant raw materials the total extractable antioxidants ranged from 20.9 to 69.5 mmol (100 g)−1 DW, and the global antioxidant response ranged from 67.2 to 97.8 mmol (100 g)−1 DW. Finally, the in vitro cultures could be regarded as an antioxidant-rich alternative resource for the pharmaceutical, health food and cosmetics industries.
Highlights
Oxidation processes are inherent for the energy generation to sustain biological activity in living organisms
We have presented data on antioxidative properties and the accumulation of important secondary metabolites of selected medicinal plants
The cultures were established in the Department of Pharmaceutical Botany, Jagiellonian University, Medical College (Kraków, Poland), for details see, respectively [15,17,22]
Summary
Oxidation processes are inherent for the energy generation to sustain biological activity in living organisms. Is entangled in the origination of many chronic diseases, i.e. cancer, rheumatoid disease, atherosclerosis, and the degenerative processes associated with senescence [1,2,3,4,5]. ROS damage, synthetic and semisynthetic antioxidants are extensively used [2,6,7] but, they have been suspected to bear responsibility for cell or whole-organ (liver) injuries and carcinogenesis [8,9]. There is a great need for functional and natural antioxidants that are able to reduce ROS overproduction and slow down the advancement of many chronic diseases. Plant-derived natural antioxidants are very efficient at inhibiting the process of oxidation by neutralizing ROS. Medications derived from plant sources are considered safer than synthetics [10]
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