Abstract

The susceptibilities of 317 gram-negative bacilli to cefpiramide, cefotaxime, and piperacillin were determined by standardized microdilution and disk diffusion tests. Cefpiramide and piperacillin were more consistently active against nonfermenters than against Enterobacteriaceae , whereas cefotaxime was more active against Enterobacteriaceae . Inhibitory zone diameters of ∼75-μg cefpiramide disks correlated well with minimal inhibitory concentrations ( r = 0.85); breakpoints for defining susceptibility and resistance were recommended.

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