Abstract

Pharmacokinetic concerns in the management of drug induced vomiting in co-morbid tuberculosis patient: A case report from MalaysiaAtif M, Sulaiman SAS, Shafie AA, Muttalif AR4, Ali I, Saleem F

Highlights

  • One-third of the global population has been latently infected with TB (LoBue et al, 2009)

  • A computational study was carried out to target 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Isopentenyl pyrophosphate (IspD), an enzyme of the methylerythritol phosphate pathway that is essential for mycobacterial survival

  • The World Health Organization. PDB (WHO) reported that an estimated 10 million people fell ill with TB worldwide, and India accounted for 27% of the global TB cases in the year 2018 (World Health Organization, 2019)

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Summary

Introduction

One-third of the global population has been latently infected with TB (LoBue et al, 2009). The WHO reported that an estimated 10 million people fell ill with TB worldwide, and India accounted for 27% of the global TB cases in the year 2018 (World Health Organization, 2019). TB is predominantly an infectious disease caused by a group of mycobacterial species called Mycobacterium tuberculosis complex. It is primarily a pulmonary pathogen but can infect other parts of the human body (Jassal and Bishai, 2009; Kumar et al, 2017c).

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