Abstract
To the Editor: We appreciate the commentary of Drs. Oymak and Onal on our analysis of the impact of prostate size on severe acute genitourinary toxicity in patients treated with intensity-modulated radiation therapy for prostate cancer ( 1 Aizer A.A. Anderson N.S. Oh S.C. et al. The impact of pretreatment prostate volume on severe acute genitourinary toxicity in prostate cancer patients treated with intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2011; 79: 379-384 Abstract Full Text Full Text PDF PubMed Scopus (28) Google Scholar ). Their insights into our work are well conceived and articulated, and we appreciate the opportunity to respond to their questions and comments. Response to “The Impact of Pretreatment Prostate Volume on Severe Acute Genitourinary Toxicity in Prostate Cancer Patients Treated With Intensity-Modulated Radiation Therapy” (Int J Radiat Oncol Biol Phys 2011;79:379–384)International Journal of Radiation Oncology, Biology, PhysicsVol. 80Issue 5PreviewTo the Editor: We read with great interest the article by Aizer et al. (1). In this study, the authors analyzed 214 patients with prostate cancer and found that patients with larger prostates (>50 cm3) are at higher risk for the development of severe acute genitourinary toxicity when treated with intensity-modulated radiation therapy for prostate cancer. In fact, the effect of prostate volume on genitourinary toxicity has been vigorously investigated for prostate brachytherapy, but studies of the effect of prostate volume on toxicity related to external-beam radiotherapy are relatively scarce. Full-Text PDF
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