Improving Foot Rocker via Robot-Resisted Gait Training With Self-Awareness Biofeedback in Adults With Cerebral Palsy.

Categorization of gait patterns in adults with cerebral palsy: A clustering approach

Objectives: To investigate the effects of rhythmic auditory stimulation (RAS) on gait patterns in comparison with changes after neurodevelopmental treatment (NDT/Bobath) in adults with cerebral palsy. Design: A repeated-measures analysis between the pretreatment and posttreatment tests and a comparison study between groups. Setting: Human gait analysis laboratory. Subjects: Twenty-eight cerebral palsy patients with bilateral spasticity participated in this study. The subjects were randomly allocated to either neurodevelopmental treatment (n = 13) or rhythmic auditory stimulation (n = 15). Interventions: Gait training with rhythmic auditory stimulation or neurodevelopmental treatment was performed three sessions per week for three weeks. Temporal and kinematic data were analysed before and after the intervention. Rhythmic auditory stimulation was provided using a combination of a metronome beat set to the individual’s cadence and rhythmic cueing from a live keyboard, while neurodevelopmental treatment was implemented following the traditional method. Main measures: Temporal data, kinematic parameters and gait deviation index as a measure of overall gait pathology were assessed. Results: Temporal gait measures revealed that rhythmic auditory stimulation significantly increased cadence, walking velocity, stride length, and step length (P < 0.05). Kinematic data demonstrated that anterior tilt of the pelvis and hip flexion during a gait cycle was significantly ameliorated after rhythmic auditory stimulation (P < 0.05). Gait deviation index also showed modest improvement in cerebral palsy patients treated with rhythmic auditory stimulation (P < 0.05). However, neurodevelopmental treatment showed that internal and external rotations of hip joints were significantly improved, whereas rhythmic auditory stimulation showed aggravated maximal internal rotation in the transverse plane (P < 0.05). Conclusions: Gait training with rhythmic auditory stimulation or neurodevelopmental treatment elicited differential effects on gait patterns in adults with cerebral palsy.

Objectives: Previous research on walking patterns by stages is lacking. This research goal was to assess the influences of Forward Walking - FW and Backward Walking - BW trainings on gait pattern in adults. Methods/Statistical Analysis: There were 20 study subjects in the FW group and 20 in the BW group. The gait pattern was evaluated in all subjects in the same manner before and after the intervention, using a Gait Analyzer. Interventions were conducted for 30 minutes, 5 days a week for 4 weeks. The measured data were analyzed using t-test. Findings: The results in the FW group showed no statistical differences in the values before and after training for step time, step length and foot flat to heel off, while, in the BW group, step time (left and right), step length and foot flat to heel off (left and right) presented statistical differences pre and post training. In clinical application, BW exercise can be offered to those with deficits in these 3 elements based on analysis of gait patterns. Improvements/Applications: Future research needs an intervention by each gait element through systematic analysis of those with inappropriate gait pattern. The researcher hopes research analyzing gait patterns will be actively performed. Keywords: Adult, Backward Walking, Forward Walking, Gait Analyzer, Gait Pattern

Purpose: In the management of adults with cerebral palsy (CP), one of the goals is to monitor and prevent spasticity-related deteriorations in gait. Botulinum Toxin Injections (BTI) are commonly used to treat this spasticity in these patients. The purpose of this study was to evaluate (i) the effect of multi-site BTI on gait patterns in adults with CP and (ii) to determine if these modifications could be detected by the Gait Deviation Index (GDI). Method: Spontaneous-velocity gait was recorded using 3D gait analysis before and 1 month after multi-site BTI in lower limb muscles. Spatiotemporal parameters (STP), kinematic parameters (KP) and the GDI were computed. Results: Post BTI, stride length, peak hip flexion and peak knee flexion during Swing Phase (SW) were significantly increased while the GDI was not significantly modified. Conclusion: A single multi-site BTI improved STP and KP of adults with CP but the GDI was not sensitive enough to detect these changes.Implications for RehabilitationOnly few study on adults with cerebral palsy BTI approach on the gait patterns are largely unknown.BTI session induced only some smaller improvement of KP and STP.This improvement did not modify the GDI.We cannot determine if GDI is a relevant tool to evaluate changes following BTI or other types of treatment.

Gait training facilitates push-off and improves gait symmetry in children with cerebral palsy

The gait function in adults with cerebral palsy (CP) deteriorates rapidly with age. Dance has been used as an effective intervention to improve balance, postural control, and gait. This study aimed to investigate the feasibility and effects of an adapted dance program (ADP) on the gait in adults with CP. The ADP, which consists of floor and barre workouts, was designed to be adapted for individuals with CP. Ten female adults with spastic diplegic CP (mean age 52.3 ± 6.34, Gross Motor Function Classification System level II) participated in this study. Outcome measures, examined using 3D gait analysis, included spatiotemporal gait parameters and the Gait Deviation Index (GDI) based on nine kinematic variables in all planes of motion. To assess feasibility, we conducted post-questionnaires and a group interview. The ADP, each lasting 90 min, was held twice per week for 12 weeks. A statistically significant improvement was observed in GDI (Δ5.74 points, p = 0.014), with a large effect size (d = 0.76). Foot off (Δ-0.72%), first double support (Δ-0.2%), second double support (Δ1.5%), and single support (Δ0.64%) showed no significant differences. Step length (Δ1.48 cm), cadence (Δ3.95 steps/min), and walking speed (Δ6.41 cm/s) tended to increase, though the differences were not statistically significant. Participants expressed high levels of physical and emotional satisfaction, suggesting a need for early intervention. The ADP may improve gait patterns in adults with spastic diplegic CP. The feasibility results indicated that the ADP is suitable for adults with spastic diplegic CP. This study provides evidence for improvement in gait patterns through dance, which has not been reported in previous dance studies on individuals with CP, offering additional information on the benefits of dance.

Aim To determine if robotic gait training for individuals with cerebral palsy is more effective than the standard of care for improving function. Method PubMed, Embase, Scopus, and Cochrane databases were searched from 1980–January, 2022 for articles that investigated robotic gait training versus standard of care (i.e. physical therapy or standard gait training) for individuals with cerebral palsy. Articles were included if a randomized controlled trial design was used, and excluded if robotic gait training was combined with another neuromuscular intervention, such as functional electrical stimulation. A meta-analysis of outcomes measured in at least four studies was conducted. Results Eight citations met all criteria for full-text review and inclusion in the meta-analysis. A total of 188 individuals with cerebral palsy, ages four to 35, and Gross Motor Function Classification System levels I–IV were studied. Level of evidence ranged from 2b–1b. All studies utilized a tethered, assistive device for robotic gait training. The overall effect was not significantly different between the robotic gait training and control interventions for six minute walk test performance (95% CI: −0.17, 0.73; P = 0.22), free walking speed (95% CI: −0.18, 0.57; P = 0.30), or Gross Motor Function Measures D (Standing) (95% CI: −0.29, 0.39; P = 0.77) and E (Walking, Running and Jumping) (95% CI: −0.11, 0.57; P = 0.19). Conclusion Tethered robotic devices that provide assistive gait training for individuals with cerebral palsy do not provide a greater benefit for improving mobility than the standard of care.

Purpose: We investigated if 30 min of daily treadmill training with an incline for 6 weeks would reduce ankle joint stiffness and improve active range of movement in adults with cerebral palsy (CP).Methods: The study was designed as a randomized controlled clinical trial including 32 adults with CP (GMFCS 1–3) aged 38.1 SD 12 years. The training group (n = 16) performed uphill treadmill training at home daily for 30 min for 6 weeks in addition to their usual activities. Passive and reflex mediated stiffness and range of motion (ROM) of the ankle joint, kinematic and functional measures of gait were obtained before and after the intervention/control period. Intervention subjects trained 31.4 SD 10.1 days for 29.0 SD 2.3 min (total) 15.2 h.Results: Passive ankle joint stiffness was reduced (F = 5.1; p = 0.031), maximal gait speed increased (F = 42.8, p < 0.001), amplitude of toe lift prior to heel strike increased (F = 5.3, p < 0.03) and ankle angle at heel strike was decreased (F = 12.5; p < 0.001) significant in the training group as compared to controls.Conclusion: Daily treadmill training with an incline for 6 weeks reduces ankle joint stiffness and increases active ROM during gait in adults with CP. Intensive gait training may thus be beneficial in preventing and reducing contractures and help to maintain functional gait ability in adults with CP.Implications for rehabilitationUphill gait training is an effective way to reduce ankle joint stiffness in adult with contractures.6 weeks of daily uphill gait training improves functional gait parameters such as gait speed and dorsal flexion during gait in adults with cerebral palsy.

BackgroundThe project proposes three innovative intervention techniques (treadmill training, mobility training with virtual reality and transcranial direct current stimulation that can be safely administered to children with cerebral palsy. The combination of transcranial stimulation and physical therapy resources will provide the training of a specific task with multiple rhythmic repetitions of the phases of the gait cycle, providing rich sensory stimuli with a modified excitability threshold of the primary motor cortex to enhance local synaptic efficacy and potentiate motor learning.Methods/designA prospective, double-blind, randomized, controlled, analytical, clinical trial will be carried out.Eligible participants will be children with cerebral palsy classified on levels I, II and III of the Gross Motor Function Classification System between four and ten years of age. The participants will be randomly allocated to four groups: 1) gait training on a treadmill with placebo transcranial stimulation; 2) gait training on a treadmill with active transcranial stimulation; 3) mobility training with virtual reality and placebo transcranial stimulation; 4) mobility training with virtual reality and active transcranial stimulation. Transcranial direct current stimulation will be applied with the anodal electrode positioned in the region of the dominant hemisphere over C3, corresponding to the primary motor cortex, and the cathode positioned in the supraorbital region contralateral to the anode. A 1 mA current will be applied for 20 minutes. Treadmill training and mobility training with virtual reality will be performed in 30-minute sessions five times a week for two weeks (total of 10 sessions). Evaluations will be performed on four occasions: one week prior to the intervention; one week following the intervention; one month after the end of the intervention;and 3 months after the end of the intervention. The evaluations will involve three-dimensional gait analysis, analysis of cortex excitability (motor threshold and motor evoked potential), Six-Minute Walk Test, Timed Up-and-Go Test, Pediatric Evaluation Disability Inventory, Gross Motor Function Measure, Berg Balance Scale, stabilometry, maximum respiratory pressure and an effort test.DiscussionThis paper offers a detailed description of a prospective, double-blind, randomized, controlled, analytical, clinical trial aimed at demonstrating the effect combining transcranial stimulation with treadmill and mobility training on functionality and primary cortex excitability in children with Cerebral Palsy classified on Gross Motor Function Classification System levels I, II and III. The results will be published and will contribute to evidence regarding the use of treadmill training on this population.Trial registrationReBEC RBR-9B5DH7

Effects of robotic gait rehabilitation on biomechanical parameters in the chronic hemiplegic patients

Purpose With few treatment options available for non-ambulatory children with cerebral palsy (CP), a robotic lower extremity gait trainer may provide a non-invasive addition to conventional treatment options. This case study investigates the usage and impact of robotic lower extremity gait trainer use in a participant with CP over the initial 3 months of use. Materials and methods This prospective case study involves a 7-year old female (GMFCS V) with CP (registered clinical trial: NCT04251390). The participant used a Trexo Home robotic gait trainer (Trexo) in the community with assessments occurring in the home and school. Trexo usage and bowel movements (BMs) were tracked daily. Postural control and lower extremity range of motion (ROM) and spasticity were evaluated prior to Trexo use and weekly to biweekly thereafter. Results The participant used the device an average of 46 min/week, over 3.3 d/week. BM frequency increased from 0.4/d at baseline, to 1.2 (±0.5)/d during Trexo use. There were no diffuse systematic changes in postural stability, ROM or muscle spasticity, but specifically head control and spasticity in the knee flexors had improvements. Conclusions Data and anecdotal reports suggest that regular use of the Trexo Home robotic gait trainer has positive outcomes on frequency and quality of BMs, and may improve head control, and knee flexor spasticity. Larger controlled studies are needed to evaluate the impacts of Trexo use in children with CP. Implications for Rehabilitation Non-ambulatory children with CP can use and may experience benefits from using a robot-assisted gait trainer (RAGT). Constipation, aspects of balance and focal spasticity may improve.

PurposeChildren with spastic cerebral palsy (CP) classified as Gross Motor Function Classification System (GMFCS) level IV face profound mobility limitations and are often excluded from intensive gait rehabilitation programs due to the severity of their impairments. Robotic-assisted gait training offers a promising avenue for functional improvement in this underserved population, yet empirical evidence remains scarce. This protocol describes a trial designed to evaluate the effects of a 6-month robotic gait training intervention on gross motor function, walking capacity, joint range of motion, muscle morphology, and psychological satisfaction in children with GMFCS level IV CP. Results will be reported in a subsequent publication following trial completion.MethodsThis two-arm, parallel-group, randomized controlled trial will enroll 36 children aged 6–12 years with GMFCS level IV CP. Participants will be randomized 1:1 to either the intervention group (robotic gait training using the RoboCT Pediatric Lower Limb Rehabilitation Robot) or the control group (usual care as determined by family preference). The intervention group will receive 45-min sessions, three times per week for 24 weeks. Primary outcomes include Gross Motor Function Item Set and walking capacity (1-min walk test). Secondary outcomes include passive ankle joint range of motion, lower-limb muscle morphology via ultrasound, and psychological satisfaction. Linear mixed-effects models will evaluate group-by-time effects under an intention-to-treat framework.DiscussionThis will be one of the first trials to explore long-term robotic gait training in children with GMFCS level IV CP. Findings may inform evidence-based rehabilitation approaches and improve access to technology-supported interventions in this highly underserved population.Clinical trial registrationClinicalTrials.gov, NCT07049523.

To identify the gait parameters used to assess gait disorders in children with bilateral spastic cerebral palsy (CP) and evaluate their responsiveness to treatments. A systematic search within PubMed, Web of Science, and Scopus (in English, 2000-2016) for randomized controlled trials of children with bilateral spastic CP who were assessed by instrumented gait analysis (IGA) was performed. Data related to participants and study characteristics, risk of bias, and outcome measures were collected. A list of gait parameters responsive to clinical interventions was obtained. Twenty-one articles met the inclusion criteria. Eighty-nine gait parameters were identified, 56 of which showed responsiveness to treatments. Spatiotemporal and kinematic parameters were widely used compared to kinetic and surface electromyography data. The majority of responsive gait parameters were joint angles at the sagittal plane (flexion-extension). The IGA yields responsive outcome measures for the gait assessment of children with bilateral spastic CP. Spatiotemporal and kinematic (at sagittal plane) parameters are the gait parameters used most frequently. Further research is needed to establish the relevant gait parameters for each clinical problem. Fifty-six responsive gait parameters for children with bilateral spastic cerebral palsy were identified. Most responsive gait parameters belong to joint angles time-series at sagittal plane. Spatiotemporal and kinematic parameters are widely used compared to kinetic and surface electromyography parameters.

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Background and objectives: The Honda Walking Assistive device® (HWA) is a light and easy wearable robot device for gait training, which assists patients’ hip flexion and extension movements to guide hip joint movements during gait. However, the safety and feasibility of robot-assisted gait training after total hip arthroplasty (THA) remains unclear. Thus, we aimed to evaluate the safety and feasibility of this gait training intervention using HWA in a patient who underwent THA. Materials and methods: The patient was a 76-year-old woman with right hip osteoarthritis. Gait training using HWA was implemented for 20 sessions in total, five times per week from 1 week to 5 weeks after THA. Self-selected walking speed (SWS), step length (SL), cadence, timed up and go (TUG), range of motion (ROM) of hip extension, and hip abduction and extension torque were measured preoperatively, and at 1 (pre-HWA), 2, 3, 4, 5 (post-HWA), and 10 weeks (follow-up) after THA. The gait patterns at SWS without HWA were measured by using three-dimensional (3D) gait analysis and an integrated electromyogram (iEMG). Results: The patient completed 20 gait training sessions with no adverse event. Hip abduction torque at the operative side, hip extension torque, SWS, SL, and cadence were higher at post-HWA than at pre-HWA. In particular, SWS, TUG, and hip torque were remarkably increased 3 weeks after THA and improved to almost the same levels at follow-up. Maximum hip extension angle and hip ROM during gait were higher at post-HWA than at pre-HWA. Maximum and minimum anterior pelvic tilt angles were lower at post-HWA than at pre-HWA. The iEMG of the gluteus maximus and gluteus medius in the stance phase were lower at post-HWA than preoperatively and at pre-HWA. Conclusions: In this case, the gait training using HWA was safe and feasible, and could be effective for the early improvement of gait ability, hip function, and gait pattern after THA.