Abstract
Frequency-swept pulses are extensively used in magnetic resonance spectroscopic techniques for the robust manipulation of spins across wide ranges of offset frequencies in the presence of B1 field variations. Nevertheless, designing pulse sequences consisting of multiple frequency-swept pulses can be challenging, as they often require specific timings and parameter tweaking. In the present work we discuss a simple and general approach for constructing such sequences. We present new and improved pulse sequences for applications including broadband B1-tolerant CPMG (CHORUS-CPMG), broadband chirped excitation with suppression of homonuclear J-modulation (PROCHORUS), and the further compression of frequency-swept pulse sequences by superposition of pulses which reduces pulse sequence durations by 25–40%. All sequence design strategies are accompanied by mathematical presentations, experimental results, and supporting simulations.
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