Abstract

Aim: We investigated the relationship between the severity of reciprocal ST depression and the extent of coronary artery disease in patients with inferior myocardial infarction. Method: Ninety-five consecutive patients (52 women 43 men, with a mean age of 54±5 years) who had acute inferior myocardial infarction were included in the study. Reciprocal changes in the ST segment were defined as ST depression of >1 mm in at least two out of four of the precordial leads V1–V4. All the patients had undergone coronary angiography within seven days of admission. The extension of coronary artery disease which was measured by Gensini and Reardon scores, was compared with the reciprocal changes on ECG recorded at the time of admission. Result: There was a significant correlation between reciprocal ST depression and disease extension (r=0.68 for Gensini score, r= 0.88 for Reardon score, p<0.05 for both). Conclusion: The presence of ST segment depression in the precordial leads during the acute inferior myocardial infarction was associated with greater myocardial necrosis and more frequent left coronary artery disease.

Highlights

  • The presence of ST segment depression in the precordial leads during the acute inferior myocardial infarction was associated with greater myocardial necrosis and more frequent left coronary artery disease

  • Over the past 2 decades, the 12-lead electrocardiogram (ECG) has attained special significance for the diagnosis and triage of patients with chest pain because timely detection of myocardial injury and a rapid assessment of myocardium at risk proved pivotal to implementing effective reperfusion therapies during acute myocardial infarction [1]

  • Anterior Reciprocal ST segment depression (RSTD) accompanying acute inferior myocardial infarction was shown to be attributable to the co-existent left anterior descending artery (LAD) disease [4,5], lower left ventricular ejection fraction (LVEF) [6,7] and poor prognosis

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Summary

Introduction

Over the past 2 decades, the 12-lead electrocardiogram (ECG) has attained special significance for the diagnosis and triage of patients with chest pain because timely detection of myocardial injury and a rapid assessment of myocardium at risk proved pivotal to implementing effective reperfusion therapies during acute myocardial infarction [1]. Reciprocal ST segment depression (RSTD) is a well known ECG sign often accompanying ST segment elevation myocardial infarction (STEMI). Its significance and prognostic value have been the subject of many reports. Anterior RSTD accompanying acute inferior myocardial infarction was shown to be attributable to the co-existent left anterior descending artery (LAD) disease [4,5], lower left ventricular ejection fraction (LVEF) [6,7] and poor prognosis. This study was conducted to investigate the relationship between the severity of RSTD and the extent of coronary artery disease

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