Abstract
Realizing the promise of chiral inorganic nanomaterials hinges on improving their structural stability under various chemical and environmental conditions. Here, we examine the stability of 1-D gold nanoparticle (Au NP) single helices prepared using the amphiphilic peptide conjugate Cx-(PEPAuM-ox)2 (PEPAuM-ox = AYSSGAPPMoxPPF; x = 16-22). We present a general template-independent strategy of tuning helix stability that relies on controlling the dimensions of constituent NPs. As NP dimensions increase, Au NP single helices become both more thermally stable and more stable in the presence of chemical denaturants and protein digestion agents (e.g., urea and proteinase K, respectively). We use this strategy for imparting helix stability to create colloidal suspensions of thermally robust Au NP single helices which maintain their plasmonic chiroptical activity up to ∼80 °C.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Langmuir : the ACS journal of surfaces and colloids
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.