Abstract

A decrease in lacrimal and salivary gland secretion is a primary cause of dry eye and dry mouth. Sjogren’s syndrome is the leading cause of the aqueous tear-deficient type of dry eye. 1-3 It is an autoimmune disease occurring almost exclusively in females (> 90%) and involves an extensive lymphocytic infiltration of the lacrimal and salivary glands as well as destruction of epithelial cells. 1-3 No cure exists for this disease. Moreover, its exact etiology is largely unknown, but may involve numerous factors including those of viral, endocrine, neural, genetic and environmental origin. 2-4-5

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