Impacto do Escore de Desnutrição-Inflamação na sobrevida de pacientes em hemodiálise

Abstract

Introduction: The protein-energy malnutrition is found in a large proportion in dialysis patients. The malnutrition-inflammation score (MIS) seems to be the most appropriate integrated method for assessing the nutritional status or nutritional risk of these patients. The aim of the study is to evaluate the MIS, in the diagnostic accuracy for the assessment of malnutrition, and its correlation with the survival time of patients in hemodialysis (HD). Methods: Study carried out in HD units in the city of Curitiba, Brazil, from January 2013 to December 2015. Clinical, laboratory and anthropometric data were evaluated. The data comparison between patients was made according to the t-test and the chi-square. The Kaplan-Meier curve was constructed to assess the influence of MIS on patient survival and log rank tests were used to verify the equality of survival distributions in these groups. Results: 113 HD patients were evaluated, 74% male. From the multivariable proportional hazards model (Cox regression), the MIS> 5 was a predictor of mortality, as well as creatinine <7 mg/dl and vascular access via HD catheter. In Kaplan-Meier survival analysis, patients with MIS <5 had a significantly higher survival rate. It was also possible to confirm a significant association between creatinine <7 mg/dl and catheter vascular access, and mortality. Conclusion: MIS is an independent predictor of mortality in HD patients. The cutoff 5 was able to predict mortality