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Abstract
Plain Language SummaryThe etiology of low birth weight has been related to different factors, including maternal health status, nutritional intake during pregnancy, social-economic conditions, and environmental exposures. Recently, a major area of interest has been the role of maternal systemic inflammation and its impact on the pregnancy. In particular, different hematological markers, easily derived from routine blood tests, offer a novel perspective on the inflammation status. By integrating these different markers into a composite analysis, this research provides a new perspective of the multifaceted nature of maternal inflammation and its potential impact on fetal development as reflected in birth weight. This study highlighted a negative impact of a composite inflammatory index on fetal weight and head circumference at birth. This correlation suggests the potential application of the indirect inflammatory index in clinical setting. Further research is required to assess the relationship between these markers and their use in clinical practice, enhancing their routine clinical adoption.
Published Version
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