Abstract

BackgroundThe impact of comorbidity on the risk of revision in patients undergoing Total Knee arthroplasty (TKA) and Total Hip Arthroplasty (THA) is not currently well known. The aim of this study was to analyze the impact of comorbidity on the risk of revision in TKA and THA.MethodsPatients recorded in the Catalan Arthroplasty Register (RACat) between 01/01/2005 and 31/12/2016 undergoing TKA (n = 49,701) and THA (n = 17,923) caused by osteoarthritis were included. As main explanatory factors, comorbidity burden was assessed by the Elixhauser index, categorized, and specific comorbidities from the index were taken into account. Descriptive analyses for comorbidity burden and specific conditions were done. Additionally, incidence at 1 and 5 years’ follow-up was calculated, and adjusted Competing Risks models were fitted.ResultsA higher incidence of revision was observed when the number of comorbidities was high, both at 1 and 5 years for THA, but only at 1 year for TKA. Of the specific conditions, only obesity was related to the incidence of revision at 1 year in both joints, and at 5 years in TKA. The risk of revision was related to deficiency anemia and liver diseases in TKA, while in THA, it was related to peripheral vascular disorders, metastatic cancer and psychoses.ConclusionsDifferent conditions, depending on the joint, might be related to higher revision rates. This information could be relevant for clinical decision-making, patient-specific information and improving the results of both TKA and THA.

Highlights

  • The impact of comorbidity on the risk of revision in patients undergoing Total Knee arthroplasty (TKA) and Total Hip Arthroplasty (THA) is not currently well known

  • Patients with emergency indeterminable hospital admission (TKA n = 105, < 0.2%; THA n = 85, 0.5%) or for whom the type of hospital in which they were operated on was unknown (TKA n = 187, 0.4%; THA n = 62, 0.3%) were excluded from the study, yielding a total of 49,701 TKA and 17,923 THA procedures included for analysis

  • Our study suggests that the effect of comorbidity burden on revision risk tends to be lower as time passes

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Summary

Introduction

The impact of comorbidity on the risk of revision in patients undergoing Total Knee arthroplasty (TKA) and Total Hip Arthroplasty (THA) is not currently well known. Total knee and hip arthroplasties (TKA and THA) are safe, successful, and cost-effective treatments for late-stage osteoarthritis in the knee and hip that offer pain relief, better function and improved quality of life to the patient [1,2,3,4,5]. These procedures have increased worldwide in the last few decades [2, 6] and are expected to rise due to the increase in life. Late revisions are becoming more common for patients, given the finite life of an implant, coupled with the increased use of THA in younger patients [15]

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