IMPACT OF ADULT-TO-ADULT LIVING DONOR LIVER TRANSPLANTATION PROGRAM ON PATIENTS SURVIVAL: A FRENCH 5 YEAR SINGLE CENTER EXPERIENCE

Abstract

A152 Aims: In France, the number of liver transplant patients directly depends on cadaveric graft procurement. Waiting time before liver transplantation (LT) dramatically increased during the past recent years, because of graft scarcity and of an increasing number of candidates. This situation led us to start an adult-to-adult living donor liver transplantation (AALDLT) program in 1998 in our center. The aim of this retrospective study was to compare the outcome of all adult patients put on the waiting list between 1998 and 2003 with respect of the graft used: cadaveric vs living donor. Patients and Methods: Between January 1998 and September 2003, 430 patients were put on waiting list in our center. AALDLT was performed in 32 cases (7.4%). This population was compared to the group of 266 adults who had had cadaveric LT (CLT) according to clinical and biological parameters at the time of listing, on the waiting list. One year survival from the time being on the waiting list and after LT was assessed for each group. Results: Comparison of patients with AALDLT and CLT is summarized in the Table.Figure* Significant difference Conclusion: Our results strongly suggest that an adult-to-adult living donor LT is efficient and, is able to improve the access to LT by reducing the waiting time and pre-transplant mortality. Moreover, patient survival was excellent in spite of their worse condition compared with that of patients having CLT.