Abstract
Background: Papillary thyroid carcinoma (PTC) is the commonest thyroid cancer. Cases in category-5a of Bethesda system (suspicious for papillary carcinoma) are treated by surgical lobectomy followedby total thyroidectomy if histopathology confirms papillary carcinoma. In order to reduce surgicalprocedures to one this was conducted.Objectives: evaluation of role of immunohistochemistry in pre-operative diagnosis of papillary thyroidcarcinoma on cell blocks.Materials and Method: Cell blocks were taken from cases labelled category-5a for histopathology andimmunohistochemistry using three markers (CK-19, Thyro-peroxidase, and BRAFv600E mutation).Results: were highly sensitive, and specific. The use of more than markers increases sensitivity of theprocedure.Conclusion: immunohistochemical stains on cell blocks is a reliable method for pre-operative diagnosisof papillary thyroid carcinoma.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
