Abstract

Abstract : An antigen, designated PP, common to Pasteurella pestis and Pasteurella pseudotuberculosis, has been isolated free of antigens detectable by gel diffusion. It will protect guinea pigs against plague one day after vaccination. PP apparently is a protein lipopolyssccharide complex and is analogous to endotoxin in incroasing resistance to infection, but is nontoxic in mice and guinea pigs. PP is different from and does not contain any of the antigens that have been shown previously to protact against plague.

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