Abstract

Background: The anatomical, Physiological and biochemical adaptations to Pregnancy are well orchestrated. In certain cases departure from this normal course leads to the pregnancy being complicated. Complications that so develop, endanger the life of both mother and her unborn child. One such dreaded complication is pregnancy induced hypertension. Eclampsia is defined as the pre- eclampsia when complicated with convulsion and/ or coma. However, eclampsia usually proceeds pre-eclampsia. It is one of the leading causes of maternal and perinatal mortality as well as morbidity, throughout the world. Approximately 50000 women die worldwide each year from eclampsia. The reported mortality rate ranges from 1-20%. The perinatal mortality rate of neonates born to eclamptic mothers ranges form 1.3-3%.
 Aims: 1.To evaluates the risk factors and clinical presentation in women with imminent eclampsia preoperatively.
 
 To evaluate the risk factors and clinical presentation in women with eclampsia.
 
 Materials and Methods
 The present study will be carried out in department of Obstetrics & Gynecology and MEDICINE of National institute of medical sciences (NIMS), Jaipur from October 2012 to September 2014. The study will be conducted on the antenatal and postnatal women admitted in the in patient department of NIMS, Jaipur Study Design: Prospective and retrospective observational study. Study Period October 2012 to September 2014. All the women are evaluated for demographic data, antenatal history, obstetric history, menstrual history, medical and surgical history, mode of delivery, onset of eclampsia, treatment received and maternal and fetal complications.
 Result: From the present study, it can be concluded that the age group 21-30 years is most prone for eclampsia and imminent eclampsia and the disease severity is higher in age group less than 30 years. Low socioeconomic status and poor educational status contribute for their increased incidence. These patients generally have higher proteinuria with headache followed by epigastria pain and vomiting. These women are mostly delivered by caesarian section and deliver low birth baby (< 2.5kg), which needs immediate attention and is admitted to nursery.
 Conclusion: Eclampsia and imminent eclampsia is a major health problem in pregnant women. And it carries high morbities and mortality. Eclampsia is more complicated than imminent Eclampsia.
 Keywords: Eclampsia, hypertension, preeclampsia, proteinuria

Highlights

  • The anatomical, physiological and biochemical adaptations to pregnancy are well orchestrated

  • Result: From the present study, it can be concluded that the age group 21-30 years is most prone for eclampsia and imminent eclampsia and the disease severity is higher in age group less than 30 years

  • Low socioeconomic status and poor educational status contribute for their increased incidence

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Summary

Introduction

The anatomical, physiological and biochemical adaptations to pregnancy are well orchestrated. Complications that so develop, endanger the life of both the mother and her unborn child. One such dreaded complication is pregnancy induced hypertension. Eclampsia is still commonly perceived as the end of a linear spectrum that stretches from normal pregnancy, though mild hypertension, Preeclampsia and eclampsia. Incidence of eclampsia is variable in different parts of world. 50,000 women die worldwide each year from eclampsia. The reported maternal mortality rate ranges from 1-20%. The perinatal mortality rate of neonates born to eclamptic mothers ranges from 1.3-3%. Most of these deaths are from developing nations. While it is on decline in developed countries, it is still one of the principle causes of maternal morbidity and mortality in developing countries like India

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