Abstract
BackgroundIn the last years Italy is confronting with massive migratory movements from developing countries where hemoglobinopathies are widespread. This is causing a large diffusion and a changing spectrum in the epidemiology of hemoglobin disorders in Italy.MethodsInvestigations recently published in Italy on hemoglobinopathies among immigrants were revised in order to appreciate the impact of immigration from developing countries on epidemiology of these pathologies and to outline adequate guidelines of prevention.ResultsAlthough in Italy there is a limited number of investigations regarding the relation between immigration and hemoglobin disorders, published data show that in our Nation there is a changing and increasing spectrum of hemoglobinopathies linked to immigration.ConclusionsProspective and retrospective actions of public healthy preventive policy are requested, based upon information (health educational programs for immigrants and caregivers), screenings among immigrants (school screening, pre-marital, preconception and early pregnancy screening, newborn screening), counseling for foreign at-risk couples and healthy carriers.
Highlights
In the last years Italy is confronting with massive migratory movements from developing countries where hemoglobinopathies are widespread
The inherited disorders of hemoglobinopathies are among the most common monogenic diseases in the world, and about 4,5 % of all human beings carry a gene for these abnormalities [1,2]
Sickle Cell Disease (SCD) is by far the most common and is mainly widespread in Sub-Saharan Africa, Middle-East, India and in people of African ancestry living in Europe, North, Central and South America [3,4]
Summary
In the last years Italy is confronting with massive migratory movements from developing countries where hemoglobinopathies are widespread.
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