Abstract
Multicystic encephalomalacia is diffuse lesion in which cerebral parenchyma is replaced by cysts of varying size in perinatal period. The prognosis is grave and prompt recognition with neurosonography at birth may affect further management. We present case report of infant showing multicystic spaces in brain secondary to hypoxic insult.
Highlights
Multicystic encephalomalacia (MICE) is a condition defined anatomically by the presence of multiple cavities in the greater part of both cerebral hemispheres, generally seen in the first year of life
The posterior fossa is spared with usually no connection to the ventricular system
Neurosonography has been described as the primary investigative modality and is considered superior to CT2
Summary
Multicystic encephalomalacia (MICE) is a condition defined anatomically by the presence of multiple cavities in the greater part of both cerebral hemispheres, generally seen in the first year of life. It is associated with profound neuromotor delay and consequent grave prognosis. The posterior fossa is spared with usually no connection to the ventricular system. It may be clinically silent; and is discovered when the infant fails to achieve the early milestones of neuromotor development. Various causes which include asphyxia, meningitis and twin-to-twin transfusion are responsible for this disorder[1]. Neurosonography has been described as the primary investigative modality and is considered superior to CT2
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