Abstract
Recent successful endovascular stroke trials have provided unequivocal support for these therapies in selected patients with large-vessel occlusive acute ischemic stroke. In this piece, we briefly review these trials and their utilization of advanced neuroimaging techniques that played a pivotal role in their success through targeted patient selection. In this context, the unique challenges and opportunity for advancement in current stroke networks’ routine delivery of care created by these trials are discussed and recommendations to change current national stroke system guidelines are proposed.
Highlights
Specialty section: This article was submitted to Stroke, a section of the journal Frontiers in Neurology
As a consequence of these trials’ requisite inclusion of vascular imaging, their image profiles reflected a more comprehensive, informative assessment of acute stroke than those obtained in routine clinical practice: one of tissue status and of vascular status
Because these trials enrolled patients with large-vessel occlusion (LVO) across a wide range of clinical scenarios, their results demonstrated that acute stroke imaging profiles enhanced with vascular status invaluably expanded eligibility for and established treatment of LVO-acute ischemic stroke (AIS) in its diverse array of clinical impairment beyond what routine practice has offered
Summary
Specialty section: This article was submitted to Stroke, a section of the journal Frontiers in Neurology. Recent clinical trials have endorsed a variety of advanced neuroimaging approaches to reiterate the unequivocal superiority of combined thrombolytic and endovascular therapy for improving outcomes in acute ischemic stroke (AIS) patients with large-vessel occlusion (LVO).
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