Abstract
Erythema nodosum (EN) is a dermatosis of unclear etiology, which is characterized by vascular lesion of the skin; it shows itself as hard painful nodes occurring in the derma or subcutaneous fat on the shins and thighs. EN has been described in many chronic infectious processes with some features of its clinical course. In most cases, the disease is regarded as a nonspecific immunoinflammatory response to a wide spectrum of etiological factors, including that in gestation, which presents certain problems in curing the patient. The example given below supports the need for timely testing for infectious markers in pregnancy and, in case of evolving EN, for using not only nonsteroidal anti-inflammatory drugs, but also pathogenetic treatment.
Highlights
Erythema nodosum (EN) is a dermatosis of unclear etiology, which is characterized by vascular lesion of the skin; it shows itself as hard painful nodes occurring in the derma or subcutaneous fat on the shins and thighs
EN has been described in many chronic infectious processes with some features of its clinical course
The disease is regarded as a nonspecific immunoinflammatory response to a wide spectrum of etiological factors, including that in gestation, which presents certain problems in curing the patient
Summary
Erythema nodosum (EN) is a dermatosis of unclear etiology, which is characterized by vascular lesion of the skin; it shows itself as hard painful nodes occurring in the derma or subcutaneous fat on the shins and thighs. В большинстве случаев заболевание расценивается как неспецифический иммуновоспалительный ответ на широкий круг этиологических факторов: инфекцию (стрептококк, туберкулез, лепра, сифилис, микозы, вирусы), лекарственные препараты, беременность, а также при заболеваниях с патологией иммунной системы – саркоидоз, болезни кишечника, злокачественные новообразования, ревматические заболевания [1,2,3,4,5,6,7]. С учетом течения и активности стопных суставов, плотный отек голеней, повышенную заболевания впервые был назначен метипред 8 мг/сут на 1 мес, температуру тела – 37,5°С.
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