Abstract

THE McManus (1946) periodic acid-Schiff (PAS) technique and the Gomori (1950) aldehyde fuchsin stain have been employed successfully in demonstrating and elucidating the histophysiology of 3 types of pituitary gland basophils (Halmi, 1950; Pearse, 1952; Purves and Griesbach, 1955). Among other cytological and histochemical methods applied to this gland, several silver impregnation methods (Bodian protargol, Gros-Schultz, Masson) will selectively demonstrate certain cells in the pars distallis (Hamperl, 1932; Biondi, 1936; Morita, 1937; Popoff, 1943; Dawson and Barnett, 1944; Hellweg, 1951; Knigge, 1955a). The identity of the cell which exhibits this property of reducing silver has not been definitely established. Popoff (1943) suggested that argyrophilic cells represented both acidophils and basophils in a resting or non-secretory phase. Hellweg (1951), applying the protargol method to human glands, demonstrated several types of argyrophilic cells on the basis of cell size and the number and size of black...

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