Abstract
(Poly(ADP-ribose) polymerases consist of 18 protein family members (PARP-1 to PARP 16). These proteins are involved in DNA repair and maintenance of genomic stability (PARP 1, 2), transcriptional regulation (PARP 4), centromere function (PARP 1, 2, 3), mitotic spindle formation, structure and function of vault particles (PARP 4), telomere dynamics (Tankyrase 1–2), trafficking of endosomal vesicles (Tankyrase), apoptosis and necrosis (PARP 1). Our goal was to identify these PARP homologues using peptide mass finger printing tool.
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