Abstract

Parkinson’s disease (PD) presents with varying gait symptoms. These range from no gait issues (NG) to gait disturbance (GD) to freezing-of-gait (FOG). GD includes slowing gait, shuffling, and instability, while FOG is the inability to take a step, potentially leading to falls. Quantitative maps like diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), and neurite orientation dispersion and density imaging (NODDI) can provide an objective assessment for gait disturbances, potentially serving as non-invasive biomarkers.

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