Abstract
Heart rate variability (HRV), the beat-to-beat changes in the heartbeat, is a nested component of the heartbeat evoked potential that entrains cortical activity in perceptual and emotional-related regions. Generalized anxiety disorder (GAD) is associated with a decreased HRV suggestive of an impairment in brain-body synchrony and parasympathetic function. Our study is, thus, a targeted restoration of neurotypical parasympathetic function and brain-body synchrony. There is potential in utilizing the cross-frequency relationships between EEG and endogenous rhythms for quantifying holistic health and designing interventions targeting these substrates.
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