Abstract
Endometrial cancer is the most common gynaecologic malignancy, usually diagnosed in postmenopausal women. However, an incidence rate of 2–14% of cases consisting of women under the age of 45 years old has been reported. Multiple reports have described the conservative treatment of this tumour in selected patients with the objective of preserving fertility. In this article, we review the literature to evaluate the results of conservative treatment of endometrial cancer with hysteroscopic resection.
Highlights
Endometrial cancer is the most common gynaecologic tumour
Federation of Gynaecology and Obstetrics (FIGO) stage is the independent variable that best relates to prognosis
The majority of patients are diagnosed in the initial stages, of which 71–75% of cases with the disease limited to the uterus [2, 3] and with a five-year survival rate of 90% for stage I [3, 4]
Summary
Endometrial cancer is the most common gynaecologic tumour. Its prognosis is generally favourable, with a five-year survival rate of 84.3% for all stages [1]. Endometrial tumours in patients under 45 are often less aggressive, with characteristics suggesting favourable prognosis, since up to 18% of cases are low grade (G1), have not penetrated more than halfway through the myometrium (stage IA) and their histology is endometrioid with positive hormone receptors (type I) [6] In this way, as a consequence of different studies and research, taking into consideration that experience is limited, there remains the possibility of initiating a treatment to preserve fertility in patients who have not yet fulfilled their desire to have children. According to the data published by these two authors, a series of 20 cases with a similar surgical technique can be discussed and later analysed in detail, in which complete local tumour resection with negative margins by means of hysteroscopy was carried out. Be it because of age or nulliparity, we are dealing with a group of patients at risk for ovarian involvement for which it is mandatory to eliminate this possibility, preferably by laparoscopy, as performed in the Laurelli’s group protocol [11]
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