Abstract
Femora of growing rats were studied four weeks after unilateral sciatic nerve resection. Cortical area at the midshaft and ash-weight of the ipsilateral femur were significantly reduced. Decrease in cortical area was due mainly to diminished periosteal apposition of bone. The hypoplasia of bone induced by sciatic nerve resection was unaffected by parathyroidectomy and was not prevented by the administration of calcitonin.
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