Abstract
AbstractWalnut (Juglans regia) kernel and its oil were found to reduce serum cholesterol, triglycerides, phospholipids and total lipids in cholesterol bilesalt stressed hypercholesterolaemic rats. Kernel was as effective as its oil (unrefined or refined); thus the efficacy of kernel was due to its oil content having about 70 % polyunsaturated fatty acids. Both unrefined and refined oils having different contents of unsaponifiable matter and sterols behaved in a similar way indicating that unsaponifiable matter and sterol contents of oil were not responsible for their efficacy. There was no difference in faecal cholesterol in animals given vanaspati, walnut kernel or its oil; thus hypolipidaemic effect observed with walnut kernel or its oil could not be attributed to any differences in faecal cholesterol. Serum SGO‐T activity of animals of groups given vanaspati, walnut kernel, walnut oil and safflower oil was similar and normal. The blend of vanaspati and walnut oil (1:1) was as effective as walnut kernel and its oil. The study brings to light special value of walnut kernel as a food material in reducing serum lipid constituents.
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