Abstract
We have read with great interest the recent article “Cellular mechanism of cardiac alternans: an unresolved chicken or egg problem” by Zang and Xia (2014), published in Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). The authors proposed that both calcium handling and electrical components of cardiac cells could be the cellular mechanism of cardiac alternans, and identifying the main mechanism of cardiac alternans could help to cure targeted patients with heart failure. Here, we present a particular case, which may help you to understand our viewpoint.
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