Abstract

Guillain-Barré syndrome (GBS) is an acquired acute autoimmune polyradiculoneuropathy. Progressive motor weakness and areflexia are essential for diagnosis. But in some cases hyperreflexia can be seen. Diagnosis of GBS was made based on history and clinical findings and was supported by cerebrospinal fluid (CSF) studies and nerve conduction study (NCS). We hereby report a case of a 42-year-old male presenting with acute onset flaccid quadriparesis. There was frank hyperreflexia in all four limbs. Although reflex preservation and hyperreflexia can be noted in axonal variant of GBS in Chinese, Japanese, and European populations, it is uncommon in India.J Enam Med Col 2017; 7(2): 111-112

Highlights

  • Reflex preservation and hyperreflexia can be noted in axonal variant of Guillain-Barré syndrome (GBS) in Chinese, Japanese, and European populations, it is uncommon in India

  • Guillain-Barré syndrome (GBS) is an acquired acute inflammatory demyelinating polyradiculoneuropathy (AIDP), which manifests as areflexic, flaccid paralysis with variable sensory disturbances, and increased cerebrospinal fluid (CSF) protein without pleocytosis i.e. albumino-cytological dissociation

  • Axonal GBS has been subclassified into acute motor axonal neuropathy (AMAN) and acute motor and sensory axonal neuropathy (AMSAN)

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Summary

Introduction

Guillain-Barré syndrome (GBS) is an acquired acute inflammatory demyelinating polyradiculoneuropathy (AIDP), which manifests as areflexic, flaccid paralysis with variable sensory disturbances, and increased cerebrospinal fluid (CSF) protein without pleocytosis i.e. albumino-cytological dissociation. A 42-year-old male presented with complaints of acute onset flaccid weakness in all four limbs for 10 days. Past history revealed an episode of diarrhea 7−8 days back which resolved spontaneously. He was almost bed-ridden, unable to move his limbs and unable to lift his head from the bed or move from side to side following the event. Detailed neurological examination revealed a normal higher mental function without any cranial nerve involvement or neck rigidity. 1. Professor, Department of Medicine, Government Medical College/Guru Nanak Dev Hospital, Amritsar, India-143001. 2. Junior Resident, Department of Medicine, Government Medical College/Guru Nanak Dev Hospital, Amritsar, India-143001

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