Abstract
The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes. A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes. After optimizing the reaction conditions, ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction. The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes. Operational simplicity, no solvent, low cost of the catalyst, high yields, reusability, excellent chemoselectivity, wide applicability are the key features of this method.
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