Abstract
In order to obtain further information on the behaviour and optimal design of external-circulation-loop airlift bioreactors, the liquid circulating velocity was studied using highly viscous pseudoplastic solutions of starch and antibiotic biosynthesis liquids of Penicillium chrysogenum, Streptomyces griseus, Streptomyces erythreus, Bacillus licheniformis and Cephalosporium acremonium. Measurements of liquid circulation velocity were made in laboratory and pilot plant external-loop airlift bioreactors, under various conditions concerning gas flow rate, riser liquid height at constant downcomer height, A D /A R ratio, using the impulse-response technique. It has been found that these parameters had a significant effect on liquid circulation velocity together with the apparent viscosity and dry weight of the solid phase in the biosynthesis liquids. For the tested liquids, the superficial liquid velocity in the riser section of an external-loop airlift bioreactor may be described by the following equation: $$$$
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